Applications of lc ms in toxicology gives practical hands on information on applications of lc ms on different groups of drugs and poisons and in different contexts this book covers all essential theoretical aspects of liquid chromatography coupled with mass spectrometry including technical details of the instrumentation. Following the developments of lc ms in the last decade and its establishment as the method of choice in the pharmaceutical industry analytical rd the technique has gained favour in other scientific disciplines including analytical toxicology this is notably due to the fact that purchase and operative costs of the equipment have gradually decreased over the same period many scientists in . Abstract toxicological screening is the analysis of biological samples to detect and identify unknown compounds the high selectivity and sensitivity of liquid chromatography lc coupled to mass spectrometry ms or tandem mass spectrometry ms ms technology provide an attractive alternative to the current methods lc uv gc ms etc. Although many applications prove that lc ms is a valuable complementary analytical tool to gc ms and has the potential to largely extend the application field of mass spectrometry to hitherto ms phobic molecules we must recognize that the use of lc ms in forensic toxicology remains relatively rare
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